Primatologist Davis Okoye confers an enduring stick to George, the marvelously smart gorilla who has been in his care since birth. Regardless, a revolutionary genetic examination gone off to some far away place changes this fragile gorilla into an incensed animal. As these as of late influenced mammoths to tear transversely finished North America, crushing everything in their way, Okoye bunches with a defamed innate expert to secure a cure, engaging his way through a consistently developing bleeding edge, to stop an overall disaster and in addition to save the fearsome creature that was at one time his friend.